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r gnavus atcc 29149  (ATCC)


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    Structured Review

    ATCC r gnavus atcc 29149
    R Gnavus Atcc 29149, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 233 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/r+gnavus+atcc+29149/Ruminococcus+gnavus%3B+Strain+VPI+C7-9/pm41638192-244-4-6
    Average 96 stars, based on 233 article reviews
    r gnavus atcc 29149 - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    In Vitro:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.
    Article Snippet: .. In LAB, CWPS have also been reported to be the attaching point, or receptors, used by phages.231,234 Recently, CWPS have been identified in the Gram-positive human gut symbiont R. gnavus.170 R. gnavus is present from the early life of infants235–237 and persists across the lifetime as a component of the adult gut microbiota, where it is present in 90% of human faecal samples from healthy adults.238–240 In vitro, R. gnavus strains and their purified CWPS, glucorhamnan-I (characterized in R. gnavus ATCC 29149) and glucorhamnan-II (characterized in R. gnavus E1 and R. gnavus ATCC 35913) induced strain-specific production of cytokines and chemokines in bone-marrow derived dendritic cells (mBMDCs)122,123 and NF-κB activation in reporter cells.122 The synthesized pentasaccharide repeat of glucorhamnan-I was shown to be sufficient to induce an immune response and a release of inflammatory cytokines like TNF-α and IL-6 from mBMDCs through TLR4 recognition.241 Among the three strains tested (R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells.122 Bioinformatics analyses revealed the presence of a glucorhamnan biosynthesis cluster which appeared conserved across all R. gnavus strains.123 This cluster contains 23 genes and variable numbers of glycosyltransferases, suggesting that the composition of residues within the glucorhamnan structure is different among R. gnavus strains. ..

    Purification:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.
    Article Snippet: .. In LAB, CWPS have also been reported to be the attaching point, or receptors, used by phages.231,234 Recently, CWPS have been identified in the Gram-positive human gut symbiont R. gnavus.170 R. gnavus is present from the early life of infants235–237 and persists across the lifetime as a component of the adult gut microbiota, where it is present in 90% of human faecal samples from healthy adults.238–240 In vitro, R. gnavus strains and their purified CWPS, glucorhamnan-I (characterized in R. gnavus ATCC 29149) and glucorhamnan-II (characterized in R. gnavus E1 and R. gnavus ATCC 35913) induced strain-specific production of cytokines and chemokines in bone-marrow derived dendritic cells (mBMDCs)122,123 and NF-κB activation in reporter cells.122 The synthesized pentasaccharide repeat of glucorhamnan-I was shown to be sufficient to induce an immune response and a release of inflammatory cytokines like TNF-α and IL-6 from mBMDCs through TLR4 recognition.241 Among the three strains tested (R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells.122 Bioinformatics analyses revealed the presence of a glucorhamnan biosynthesis cluster which appeared conserved across all R. gnavus strains.123 This cluster contains 23 genes and variable numbers of glycosyltransferases, suggesting that the composition of residues within the glucorhamnan structure is different among R. gnavus strains. ..

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role
    Article Snippet: .. Among the three strains tested ( R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells. ..

    Derivative Assay:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.
    Article Snippet: .. In LAB, CWPS have also been reported to be the attaching point, or receptors, used by phages.231,234 Recently, CWPS have been identified in the Gram-positive human gut symbiont R. gnavus.170 R. gnavus is present from the early life of infants235–237 and persists across the lifetime as a component of the adult gut microbiota, where it is present in 90% of human faecal samples from healthy adults.238–240 In vitro, R. gnavus strains and their purified CWPS, glucorhamnan-I (characterized in R. gnavus ATCC 29149) and glucorhamnan-II (characterized in R. gnavus E1 and R. gnavus ATCC 35913) induced strain-specific production of cytokines and chemokines in bone-marrow derived dendritic cells (mBMDCs)122,123 and NF-κB activation in reporter cells.122 The synthesized pentasaccharide repeat of glucorhamnan-I was shown to be sufficient to induce an immune response and a release of inflammatory cytokines like TNF-α and IL-6 from mBMDCs through TLR4 recognition.241 Among the three strains tested (R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells.122 Bioinformatics analyses revealed the presence of a glucorhamnan biosynthesis cluster which appeared conserved across all R. gnavus strains.123 This cluster contains 23 genes and variable numbers of glycosyltransferases, suggesting that the composition of residues within the glucorhamnan structure is different among R. gnavus strains. ..

    Activation Assay:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.
    Article Snippet: .. In LAB, CWPS have also been reported to be the attaching point, or receptors, used by phages.231,234 Recently, CWPS have been identified in the Gram-positive human gut symbiont R. gnavus.170 R. gnavus is present from the early life of infants235–237 and persists across the lifetime as a component of the adult gut microbiota, where it is present in 90% of human faecal samples from healthy adults.238–240 In vitro, R. gnavus strains and their purified CWPS, glucorhamnan-I (characterized in R. gnavus ATCC 29149) and glucorhamnan-II (characterized in R. gnavus E1 and R. gnavus ATCC 35913) induced strain-specific production of cytokines and chemokines in bone-marrow derived dendritic cells (mBMDCs)122,123 and NF-κB activation in reporter cells.122 The synthesized pentasaccharide repeat of glucorhamnan-I was shown to be sufficient to induce an immune response and a release of inflammatory cytokines like TNF-α and IL-6 from mBMDCs through TLR4 recognition.241 Among the three strains tested (R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells.122 Bioinformatics analyses revealed the presence of a glucorhamnan biosynthesis cluster which appeared conserved across all R. gnavus strains.123 This cluster contains 23 genes and variable numbers of glycosyltransferases, suggesting that the composition of residues within the glucorhamnan structure is different among R. gnavus strains. ..

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role
    Article Snippet: .. Among the three strains tested ( R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells. ..

    Synthesized:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role.
    Article Snippet: .. In LAB, CWPS have also been reported to be the attaching point, or receptors, used by phages.231,234 Recently, CWPS have been identified in the Gram-positive human gut symbiont R. gnavus.170 R. gnavus is present from the early life of infants235–237 and persists across the lifetime as a component of the adult gut microbiota, where it is present in 90% of human faecal samples from healthy adults.238–240 In vitro, R. gnavus strains and their purified CWPS, glucorhamnan-I (characterized in R. gnavus ATCC 29149) and glucorhamnan-II (characterized in R. gnavus E1 and R. gnavus ATCC 35913) induced strain-specific production of cytokines and chemokines in bone-marrow derived dendritic cells (mBMDCs)122,123 and NF-κB activation in reporter cells.122 The synthesized pentasaccharide repeat of glucorhamnan-I was shown to be sufficient to induce an immune response and a release of inflammatory cytokines like TNF-α and IL-6 from mBMDCs through TLR4 recognition.241 Among the three strains tested (R. gnavus ATCC 29149, R. gnavus E1, and R. gnavus ATCC 35913), R. gnavus ATCC 35913 was found to be the most immunogenic strain, likely due to the absence of an additional capsular polysaccharide layer, while the purified glucorhamnans from the three strains showed activation of TLR4 reporter cells.122 Bioinformatics analyses revealed the presence of a glucorhamnan biosynthesis cluster which appeared conserved across all R. gnavus strains.123 This cluster contains 23 genes and variable numbers of glycosyltransferases, suggesting that the composition of residues within the glucorhamnan structure is different among R. gnavus strains. ..

    other:

    Article Title: Cell surface polysaccharides in the gut microbiota: occurrence, structure and role
    Article Snippet: R. gnavus ATCC 29149 , , EPS and CWPS , 10941 , Henke et al. .

    Functional Assay:

    Article Title: Development of the genetic toolkit identifies capsular polysaccharides as a competitive colonization factor in Ruminococcus gnavus
    Article Snippet: .. Although the previously proposed CPS cluster may be functional under specific, yet unexplored, environmental conditions, our findings indicate that the srtB4 -associated gene cluster is essential for CPS production in R. gnavus ATCC 29149. ..



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